Guanidinoacetic acid supplementation: A narrative review of its metabolism and effects in swine and poultry

Guanidinoacetic acid (GAA) is an amino derivative and precursor for creatine which plays a significant role in energy metabolism. However, because of creatine’s instability during the manufacturing process cost, GAA has been explored as effective alternative to supplements. tested potential feed additive enhance utilization growth performance poultry swine industries. Moreover, combined with methionine improve outcomes may also act arginine-sparing agent birds. The safety supplements animals, consumers, environment its efficacy numerous livestock species have proven. This narrative review discusses scientific evidence regarding metabolism effects supplementation poultry, identifying knowledge gaps future directions further research on supplementation. A systematic search literature identified published findings related their are summarized this confirm impacts performance, reproductive meat quality poultry. Amongst many demonstrated benefits, at improving body concentration, parameters, conversion ratio, animals. Although exerts non-creatine roles, including stimulation insulin secretion, neuromodulation, vasodilation, require in-depth elaboration.